Readers were most interested in learning about how new obesity agents may change treatment approaches, the metabolic consequences of obstructive sleep apnea, benefits among plant-based eating patterns and more. The approval of semaglutide (Wegovy, Novo Nordisk) has opened the door for a new approach to treat obesity, according to W. Timothy Garvey, MD, FACE, MABOM. Garvey discussed a treat-to-target approach with a focus on other cardiometabolic conditions during a presentation at the World Congress on Insulin Resistance, Diabetes & Cardiovascular Disease. Obstructive sleep apnea can predispose a person to hyperglycemia and even type 2 diabetes, yet data show continuous positive airway pressure therapy does not improve markers of glucose dysregulation. In a presentation at the Heart in Diabetes CME conference, Naresh M. Punjabi, MD, PhD, discussed how obstructive sleep apnea can impair insulin and alter free fatty acid kinetics. Among plant-based eating patterns, vegetarian and vegan diets provide the most benefits, according to a presentation from Hana Kahleova, MedicGLP Supplement MD, PhD, MBA, at the Association of Diabetes Care and Education Specialists annual meeting.
Compared with other plant-based eating patterns, such as the Mediterranean diet, vegetarian and vegan diets provide greater reductions in body weight, fat mass and LDL cholesterol and improved insulin sensitivity. The timing of eating could have an impact on cardiometabolic health, according to findings presented by Marriam Ali, MD, at the ENDO annual meeting. In analysis of data from two dietary recalls, adults who ate their first meal before 8:30 a.m. The cause of midlife migraines in women is likely multifactorial, though research suggests that fluctuating hormone levels may play a role, according to a speaker at the North American Menopause Society annual meeting. Kevin Weber, MD, MHA, discussed migraine prevalence in women and how the condition is now thought to be a neural process with many contributing factors. Using phenotype-guided obesity interventions can lead to greater weight loss for people with obesity than standard of care. In a presentation at the Obesity Medicine Association 2021 virtual conference, Andres Acosta, MD, PhD, MedicGLP Supplement described how phenotype-guided treatment can help individualize care for each person with obesity based on what is driving their disease.
A subset of patients with hypothyroidism report dissatisfaction with treatment and persistent symptoms, such as fatigue and weight gain, despite medication, according to a presenter at the ENDO annual meeting. Anne R. Cappola, MD, ScM, discussed how endocrinologists can take steps to improve treatment satisfaction for patients. The investigational glucose-dependent insulinotropic polypeptide/GLP-1 receptor agonist tirzepatide (Eli Lilly) led to significant and superior HbA1c and body weight reductions for adults with type 2 diabetes vs. SURPASS-2 study data presented at the American Diabetes Association annual meeting. Eating a very low-calorie ketogenic diet may increase testosterone levels in men with obesity, according to a small study presented at the European Congress of Endocrinology. In data presented by Angelo Cignarelli, MedicGLP MD, PhD, strong associations were observed between glucose regulation and hepatic and testicular function. Postmenopausal women with low bone mass saw greater gains in spine bone mineral density and less bone turnover when assigned monthly risedronate therapy compared with a 12-month regimen of impact and resistance exercises, according to data presented by Laura D. Bilek, PhD, PT, at the American Society for Bone and Mineral Research annual meeting.
Science continues to prove that the old adage "you are what you eat" is profoundly true. This is because you have trillions of microorganisms living in your gut, which are directly responsible for nearly every aspect of your health. These microbes make up what’s called your "gut microbiota." They are especially influential in determining your likelihood of gaining excessive weight, becoming obese, and developing obesity-related diseases like diabetes, heart disease, and premature death. The gut microbiome (the expressed genes of your gut microbiota) plays a major role in your metabolism through energy production, storage, and expenditure. So, it’s no surprise that science has found a strong connection between gut microbiome imbalance and metabolic syndrome. Yikes! If you have the wrong mix of microbes, it could be making it tough for you to get your health on track! Did you know: Scientists can actually look at your gut microbiome composition and tell with 90% accuracy if you are obese or lean. That’s pretty impressive, MedicGLP Online isn’t it?
1. Unable to lose weight and keep it off? 2. Struggling to fight cravings? 3. Sick of starving yourself for weight loss? 4. Baffled as to why no diet seems to really work for you? Depending on the composition of your gut microbiome, your microbes can either boost your health or weigh you down (figuratively and literally). The good news is this: You have control over these little guys with every bite you eat. Diet has the power to change the landscape of your gut microbiome. So, if you’ve tried multiple diets and can’t seem to get the results you want, it’s time to look into your gut microbiome.Will You Lose Weight Naturally on an Individualized Diet? If you’ve been struggling to lose weight and keep it off - it could be your gut microbiome. While Viome doesn’t guarantee weight loss, it has been an exciting result many of our customers have reported. "Fiona’s update day 37!